a bは若山氏が違うといった?胎児胎盤の写真
c STAP細胞はキメラの胎盤・卵黄のう形成に寄与するとの棒グラフ(キメラ胎児の6割に貢献)
d STAP細胞は胎児形成能を持つOct4,Nalog,Rex1を発現するが、ESとの比較で示す
およびTSマーカー(Cdx2、Eomes, Elf5)の発現についてTSとの比較で示す
e STAP 幹細胞3種は、胎盤形成に寄与しない。 TSとのGFP細胞の割合の比較
f STAP 幹細胞、ES 細胞は Cdx2、Eomes,、Elf5 マーカーを発現しない。TSとの比較
レター論文は司書の奴と翻訳機の奴が英日対訳形式でここに張り付けてるから確認したら?
>>
12: 司書 :2018/10/10(水) 10:51:31
(英文)
Here we have investigated the unique nature of STAP cells, focusing on their differentiation potential into the two major categories (embryonic and placental lineages) of cells in the blastocyst. We became particularly interested in this question after a blastocyst injection assay revealed an unexpected finding. In general, progeny of injected ES cells are found in the embryonic portion of the chimaera, but rarely in the placental portion (Fig. 1a; shown with Rosa26-GFP). Surprisingly, injected STAP cells contributed not only to the embryo but also to the placenta and fetal membranes (Fig. 1b and Extended Data Fig. 1a–c) in 60% of the chimaeric embryos (Fig. 1c).
なるほど、(Fig. 1a; shown with Rosa26-GFP)はES細胞のコンテクストの中に含まれているのね。
>>
Here we have investigated the unique nature of STAP cells, focusing on their differentiation potential into the two major categories (embryonic and placental lineages) of cells in the blastocyst. We became particularly interested in this question after a blastocyst injection assay revealed an unexpected finding. In general, progeny of injected ES cells are found in the embryonic portion of the chimaera, but rarely in the placental portion (Fig. 1a; shown with Rosa26-GFP). Surprisingly, injected STAP cells contributed not only to the embryo but also to the placenta and fetal membranes (Fig. 1b and Extended Data Fig. 1a–c) in 60% of the chimaeric embryos (Fig. 1c).
画像側には不合理な点はないんだね。本文側がこの画像と一致してないんだね。
まず(Fig. 1a; shown with Rosa26-GFP)は<shown with Rosa26-GFP>と対応させるのなら
Fig.1bでないといけない。そして本文自体がESコンテクストの中にあるので、
STAPコンテクストの中で論じられないといけないね。
これなら合理的に意味が通るのね。
>>
Here we have investigated the unique nature of STAP cells, focusing on their differentiation potential into the two major categories (embryonic and placental lineages) of cells in the blastocyst. We became particularly interested in this question after a blastocyst injection assay revealed an unexpected finding. In general, progeny of injected ES cells are found in the embryonic portion of the chimaera, but rarely in the placental portion (Fig. 1a). Surprisingly, injected STAP cells contributed not only to the embryo but also to the placenta and fetal membranes (Fig. 1b ; shown with Rosa26-GFP and Extended Data Fig. 1a–c) in 60% of the chimaeric embryos (Fig. 1c).
序でだから、若山さんの取り下げ理由も絡めて考えるといいな。
>>
(1) Figure 1a and b in the Letter both show embryos generated from STAP cells, not a comparison of ES- and STAP-derived chimaeric embryos, as indicated in the legend.
どちらも4Nと書かれているんだけどな。2Nと書かれているのはaだよ。dは4nとキャプションにあって、レターのとはしかもマウス背景も違う。
>>
(2) Extended Data Fig. 7d in the Article and Extended Data Fig. 1a in the Letter are different images of the same embryo and not, as indicated in the legends, a diploid chimaera embryo and tetraploid chimaera embryo.
これって、無茶苦茶だよな。1aはSTAP細胞キメラだと言ってるんでしょ。これの胎盤は光ってないぜ。光ってない方の増感もへったくれもないだろう。
>>
(3) There is an erroneous description in Fig. 1a in the Letter. The right panel of Fig. 1a is not a ‘long exposure’ image at the camera level but a digitally enhanced one.
こんなかしらねえ。
>>
Here we have investigated the unique nature of STAP cells, focusing on their differentiation potential into the two major categories (embryonic and placental lineages) of cells in the blastocyst. We became particularly interested in this question after a blastocyst injection assay revealed an unexpected finding.
Surprisingly, injected STAP cells contributed not only to the embryo but also to the placenta and fetal membranes (Fig. 1a; shown with Rosa26-GFP).
In general, progeny of injected ES cells are found in the embryonic portion of the chimaera, but rarely in the placental portion(Fig. 1b).
なるほど。この原稿は若山さんも知らないんだな。そして笹井さんの手に渡った時に
叙述の順番が入れ替えられた。しかし、カッコ内がそのまま残されてしまったと。
>>
Here we have investigated the unique nature of STAP cells, focusing on their differentiation potential into the two major categories (embryonic and placental lineages) of cells in the blastocyst. We became particularly interested in this question after a blastocyst injection assay revealed an unexpected finding.
In general, progeny of injected ES cells are found in the embryonic portion of the chimaera, but rarely in the placental portion(Fig. 1a; shown with Rosa26-GFP).
Surprisingly, injected STAP cells contributed not only to the embryo but also to the placenta and fetal membranes(Fig. 1b).
この原稿を若山さんが持っているということなのね。それで1aがsTAPで胎盤の光っている写真と
思い込んでる。
ところがいつの時点化で小保方さんが本文の記述順が逆になっていて、かつカッコ内が以前のままに
取り残されているということに気づいた。それで本文いじれないから写真のa,bを入れ替えて辻褄を
合わせたけどRosa26の説明がおかしくなっているということに気づかなかったのね。
でその更に後に<and Extended Data Fig. 1a–c) in 60% of the chimaeric embryos (Fig. 1c).>が
書き加えられたと。