ttp://kaken.nii.ac.jp/d/p/14570481
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Unfortunately, however, there is so far no "gold standard" assay (i.e., with 100% sensitivity and 100% specificity) for the detection of AMA in PBC.
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ttp://mice.tropmedres.ac/model103_104.aspx?model_code=MODEL104&showtab=0
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This assumes that the gold standard is perfect (100% sensitive and specific), but this is not always the case.
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ttp://www.chemistrydaily.com/chemistry/Gold_standard_(test)
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An ideal gold standard test has a sensitivity of 100% (it identifies all individuals with a disease process, and it does not have any false-negative results) and a specificity of 100% (it does not falsely identify someone with a condition that does not have the condition; it does not have any false-positive results). There are no ideal gold standard tests.
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ttp://ebem.org/definitions.html#Gold standard
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For the purposes of a study, the "gold standard" test is assumed to have 100% sensitivity and specificity.
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