最近はインシトゥハイブリダイゼイション (in situ hybridazation)などの方法で、遺伝子地図づく り (gene mapping)が行われ... http://www.rc.kyushu-u.ac.jp/￣hkoike/class/ human genome-1(chr-mapping).pdf
4：Alc良し： 検索文字列 : in situ 該当件数 : 33：2004/07/31(土) 05:42
in situ 〈ラテン語〉元［本来］の位置［場所］で、そのままで、原位置で、自然の位置で
in situ breast cancer 粘膜内の乳癌
in situ combustion 火攻法｛かこう ほう｝
in situ concrete →in-situ concrete
in situ etching →in-situ etching
in situ experiment→in-situ experiment
in situ extraction 現場抽出、埋蔵地抽出
in situ foam →in-situ foam
in situ hybridization《生化学》in situハイブリッド形成法｛けいせい ほう｝◆DNAや RNA を染色体や細胞の中から取り出さない状態で、プローブ DNA とのハイブリッド形成する技術
医学 化学 bio以外でも使うが稀のもよう。数％くらい？
（以下はサッカーの記事） http://news.ft.com/servlet/ContentServer?pagename=FT.com/StoryFT/FullStory&c=StoryFT&cid=1087374073187
And to some extent it worked. For all the foreign talent at Ranieri's disposal Chelsea's drive to the top of the Premiership was led by two Englishmen already in situ, Frank Lampard and John Terry, while Bridge was almost ever present, Johnson a regular when injury-free and Parker influential late in the season.
Britannicaの2002年版 ***************************以下引用**************************
>> infection:
>> in medicine, the invasion of the body by any of various infectious agents--including bacteria, viruses, fungi, protozoans, and worms--and the reaction of the body to them or to their toxins. When health is not altered, the process is termed a subclinical infection. When health is altered, the process is called an infectious disease.
■ 火病について
Hwa-byung (also known as wool-hwa byung): A Korean folk syndrome literally translated into English as "anger syndrome" and attributed to the suppression of anger. The symptoms include insomnia, fatigue, panic, fear of impending death, dysphoric affect, indigestion, anorexia, dyspnea, palpitations, generalized aches and pains and a feeling of a mass in the epigastrium.
Diagnostic and Statistical Manual of Mental Disorders: Dsm-IV (4th Ed)
http://d.hatena.ne.jp/finalvent/20041112#p1
Hum. Reprod. Advance Access originally published online on August 19, 2004
Human Reproduction 2004 19(11):2509-2514; doi:10.1093/humrep/deh478
The tumor necrosis factor- promoter –1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population
Tasneem Asghar1, Shigeki Yoshida1, Stephen Kennedy2, Kenichi Negoro3, Wang Zhuo1, Shinya Hamana1, Satoru Motoyama1, Satoshi Nakago1, David Barlow2 and Takeshi Maruo1,4
1 Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-Cho, chuo-ku, Kobe, 650-0017, Japan, 2 Nuffield Department of Obstetrics and Gynecology, University of Oxford, OX3 9DU, UK and 3 Department of Gastroenterology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Cho, Aoba-ku, Sendai, Miyagi, 980-8575, Japan
4 To whom correspondence should be addressed. Email: maruo@kobe-u.ac.jp
BACKGROUND: Tumor necrosis factor- (TNF-) is a multifunctional proinflammatory cytokine, associated with various inflammatory and autoimmune diseases. Elevated TNF- levels in peritoneal fluid have been reported in women with endometriosis, suggesting that TNF- may be involved in the development of endometriosis. In this study, we investigated the possible association between endometriosis and the TNF- gene promoter polymorphisms –238G/A, –308G/A, –857C/T, –863C/A and –1031T/C in a Japanese population. METHODS: We compared the distribution of the –238G/A, –308G/A, –857C/T, –863C/A and –1031T/C polymorphisms in the promoter region of TNF- in 130 endometriosis cases and 185 controls using PCR–RFLP analysis. RESULTS: The allele frequencies of –238A, –308A, –857T, –863A and –1031C in controls were 2.0%, 1.3%, 19.4%, 17.0% and 18.6%, and in the cases 1.1%, 0.3%, 19.6%, 18.6% and 13.6%, respectively. No significant differences in frequencies were found between the crude endometriosis cases and controls. However, when the endometriosis group was divided into a subgroup of women with stage IV disease only, the frequency of the –1031C allele was significantly lower in this subgroup than controls. CONCLUSIONS: The variability of the –1031T/C polymorphism of the TNF- gene may be associated with susceptibility to (AUTHOR: as meant?) endometriosis.
Key words: endometriosis/gene polymorphism/PCR/restriction fragment length polymorphism/TNF-
