どういう理由で疑問符がついているのか、分からないので原文をみてみよう https://journals.sagepub.com/doi/full/10.1177/0141076819899308
> CIN in general is likely to have been overdiagnosed in the trials because cervical cytology was
> conducted at intervals of 6–12 months rather than at the normal screeninginterval of 36 months.
> This means that the trials may have overestimated the efficacy of the vaccine
> as some of the lesions would have regressed spontaneously.