第二レフェリーのアドヴァイスね。
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The authors suggest that STAP cell-derived TS-like cells are distinct from embryo-derived TS cells, but the data for this are not decisive and could be attributed to persistent contamination with STAP cells or ES cells (which could expain the occasional Nanog positive cells). Presence of ES cells could be excluded by culture in the presenve of JAK inhibitor, and monitored by Oct4 and Nanog immunostaining. A global transcriptome anallysis could then be performed for comparison with TS cells. Data should also be provided on Fgf4 withdrawal from the TS-like cells - does this induce the expected differentiation into trophoblast giant cells?
