In particular, and of interest here, UV light mutational signatures, which are associated to NER misfunction C T or G A on complementary strand mutations, see above for molecular reasons or tobacco smoke C A or G T on complementary strand guanine substitutions occurring after exposure to benzo a pyrene contained in tobacco smoke were detected in skin and lung cancers genomes 112, 113 and were assigned number 7 and 4, respectively 91 Fig <a href=http://cialiss.cfd>buy cialis online usa</a>